@article {Shen2004,
	title = {Optimization of Biopsy Strategy by A Statistical Atlas of Prostate Cancer Distribution},
	journal = {Medical Image Analysis},
	volume = {8},
	year = {2004},
	pages = {139-150},
	author = {Dinggang Shen and Zhiqiang Lao and Jianchao Zeng and Wei Zhang and Isabel Sesterhenn and Leon Sun and Judd Moul and Edward Herskovits and Gabor Fichtinger and Christos Davatzikos}
}
@article {Shen2004a,
	title = {Optimized prostate biopsy via a statistical atlas of cancer spatial distribution},
	journal = {Medical image analysis},
	volume = {8},
	number = {2},
	year = {2004},
	month = {Jun},
	pages = {139{\textendash}150},
	abstract = {<p>A methodology is presented for constructing a statistical atlas of spatial distribution of prostate cancer from a large patient cohort, and it is used for optimizing needle biopsy An adaptive-focus deformable model is used for the spatial normalization, registration of 100 prostate histological samples, which were provided by the Center for Prostate Disease Research of the US Department of Defense, resulting in a statistical atlas of spatial distribution of prostate cancer Based on this atlas, a statistical predictive model was developed to optimize the needle biopsy sites, by maximizing the probability of detecting cancer Experimental results using cross-validation show that the proposed method can detect cancer with a 99\% success rate using seven needles, in these samples</p>
},
	keywords = {Algorithms, Biological, Biopsy, Cohort Studies, Computer Simulation, Computer-Assisted, Forecasting, Humans, Image Processing, Imaging, Male, Models, Needle, pathology, Probability, Prostate, Prostatic Neoplasms, Reproducibility of Results, Statistical, statistics /\&/ numerical data, Three-Dimensional},
	doi = {10 1016/j media 2003 11 002},
	url = {http://dx doi org/10 1016/j media 2003 11 002},
	author = {Dinggang Shen and Zhiqiang Lao and Jianchao Zeng and Wei Zhang and Isabel Sesterhenn and Leon Sun and Judd Moul and Edward Herskovits and Gabor Fichtinger and Christos Davatzikos}
}
@article {Shen2001,
	title = {Statistical Atlas Of Prostate Cancer For Optimal Biopsy},
	journal = {Lecture Notes in Computer Science Medical Image Computing and Computer-Assisted Intervention (MICCAI)},
	volume = {2208},
	year = {2001},
	pages = {416-424},
	author = {Dinggang Shen and Zhiqiang Lao and Jianchao Zeng and Edward Herskovits and Gabor Fichtinger and Christos Davatzikos}
}
@conference {Shen2001a,
	title = {Statistically optimized biopsy strategy for the diagnosis of prostate cancer},
	booktitle = {Procedings 14th IEEE Symposium on Computer-Based Medical Systems CBMS 2001},
	year = {2001},
	month = {26{\textendash}27 July},
	pages = {433{\textendash}438},
	doi = {10 1109/CBMS 2001 941758},
	author = {Dinggang Shen and Zhiqiang Lao and Jianchao Zeng and Edward Herskovits and Gabor Fichtinger and Christos Davatzikos}
}
