@conference {Heffernan2016, title = {Accuracy of lesion boundary tracking in navigated breast tumor excision}, booktitle = {SPIE Medical Imaging 2016}, volume = {9786}, year = {2016}, month = {03/2016}, pages = {97860Y-1-6}, address = {San Diego, CA, USA}, doi = {10.1117/12.2217017}, url = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=2505913\&resultClick=1}, author = {Emily Heffernan and Tamas Ungi and Thomas Vaughan and Padina Pezeshki and Andras Lasso and Gabrielle Gauvin and John Rudan and C. Jay Engel and Evelyn Morin and Gabor Fichtinger} } @conference {Ungi2016c, title = {Intraoperative user interface for navigated breast tumor surgery}, booktitle = {Computer Assisted Radiology and Surgery, 30th International Congress}, volume = {11}, year = {2016}, month = {05/2016}, pages = {S108-9}, publisher = {Springer}, organization = {Springer}, address = {Heidelberg, Germany}, doi = {10.1007/s11548-016-1412-5}, author = {Tamas Ungi and Thomas Vaughan and Gabrielle Gauvin and Padina Pezeshki and Andras Lasso and C. Jay Engel and John Rudan and Gabor Fichtinger} } @conference {Carter2016a, title = {Visual feedback mounted on surgical tool: proof of concept}, booktitle = {SPIE Medical Imaging 2016}, volume = {9786}, year = {2016}, month = {In Press}, address = {San Diego, CA, USA}, author = {Kaci Carter and Thomas Vaughan and M. Holden and Gabrielle Gauvin and Padina Pezeshki and Andras Lasso and Tamas Ungi and Evelyn Morin and John Rudan and C. Jay Engel and Gabor Fichtinger} } @article {Ungi2015b, title = {Navigated breast tumor excision using electromagnetically tracked ultrasound and surgical instruments}, journal = {IEEE Transactions on Biomedical Engineering}, year = {2015}, month = {08/2015 }, abstract = {

OBJECTIVE:

Lumpectomy, breast conserving tumor excision, is the standard surgical treatment in early stage breast cancer. A common problem with lumpectomy is that the tumor may not be completely excised, and additional surgery becomes necessary. We investigated if a surgical navigation system using intraoperative ultrasound improves the outcomes of lumpectomy, and if such a system can be implemented in the clinical environment.

METHODS:

Position sensors were applied on the tumor localization needle, the ultrasound probe, and the cautery, and three-dimensional navigation views were generated using real time tracking information. The system was tested against standard wire-localization procedures on phantom breast models by eight surgical residents. Clinical safety and feasibility was tested in six palpable tumor patients undergoing lumpectomy by two experienced surgical oncologists.

RESULTS:

Navigation resulted in significantly less tissue excised compared to control procedures (10.3 {\textpm} 4.4 vs. 18.6 {\textpm} 8.7 g, p = 0.01) and lower number of tumorpositive margins (1/8 vs. 4/8) in the phantom experiments. Excision-tumor distance was also more consistently outside the tumor margins with navigation in phantoms. The navigation system has been successfully integrated in an operating room, and user experience was rated positively by surgical oncologists.

CONCLUSION:

Electromagnetic navigation may improve the outcomes of lumpectomy by making the tumor excision more accurate.

SIGNIFICANCE:

Breast cancer is the most common cancer in women, and lumpectomy is its first choice treatment. Therefore, improvement of lumpectomy outcomes have a significant impact on a large patient population.

}, issn = {0018-9294}, doi = {10.1109/TBME.2015.2466591}, url = {http://www.ncbi.nlm.nih.gov/pubmed/26302503}, author = {Tamas Ungi and Gabrielle Gauvin and Andras Lasso and Yeo, Caitlin T and Padina Pezeshki and Thomas Vaughan and Kaci Carter and John Rudan and C. Jay Engel and Gabor Fichtinger} }